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Prevalence of Hyperhomocysteinaemia and Associated Factors among Ethiopian Adult Population in a 2015 National Survey

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dc.contributor.author Challa, Feyissa
dc.contributor.author Getahun, Tigist
dc.contributor.author Sileshi, Meron
dc.contributor.author Nigassie, Bikila
dc.contributor.author Geto, Zeleke
dc.contributor.author Ashibire, Genet
dc.contributor.author Gelibo, Terefe
dc.contributor.author Teferra, Solomon
dc.contributor.author Seifu, Daniel
dc.contributor.author Sitotaw, Yohannes
dc.contributor.author Bekele, Abebe
dc.contributor.author Abate, Ebba
dc.contributor.author Baye, Kaleab
dc.date.accessioned 2023-01-26T12:14:35Z
dc.date.available 2023-01-26T12:14:35Z
dc.date.issued 2020-01-11
dc.identifier.citation Feyissa Challa, Tigist Getahun, Meron Sileshi, Bikila Nigassie, Zeleke Geto, Genet Ashibire, Terefe Gelibo, Solomon Teferra, Daniel Seifu, Yohannes Sitotaw, Abebe Bekele, Ebba Abate, Kaleab Baye, "Prevalence of Hyperhomocysteinaemia and Associated Factors among Ethiopian Adult Population in a 2015 National Survey", BioMed Research International, vol. 2020, Article ID 9210261, 7 pages, 2020. en_US
dc.identifier.uri http://ephispace.ephi.gov.et/xmlui/handle/123456789/535
dc.description.abstract Hyperhomocy steinaemia (HHcy) is an independent risk factor for major cardiovascular diseases, but data on the prevalence and predictors of HHcy in low- and middle-income countries like Ethiopia are scant. The aim of this study was to estimate the prevalence of HHcy and associated risk factors in the Ethiopian adult population. A cross-sectional survey on risks of noncommunicable diseases (NCDs) using the STEPwise approach to surveillance (STEPS) survey was conducted between April and June 2015. A total of 4,175 study participants were surveyed. Serum homocysteine (Hcy) and metabolic profile were determined using Cobas Integra 400 Plus and CardioChek PA analyzer, respectively. Factors associated with HHcy were determined using logistic regression. The mean serum tHcy concentration was 14.6 μmol/L, with 16.4 μmol/L in males and 13.4 μmol/L in females. Overall, 38% had HHcy, with figures in males (49%) higher than females (30%). Increased age, being male, and high blood pressure and/or taking blood pressure medication, as well as low consumption of fruit and/or vegetables, were independent risk factors for HHcy. In conclusion, the prevalence of HHcy among the adult Ethiopian population is alarmingly high. Improving diets through the promotion of fruit and vegetable consumption is needed to reduce the risk of NCDs. en_US
dc.language.iso en en_US
dc.publisher EPHI en_US
dc.title Prevalence of Hyperhomocysteinaemia and Associated Factors among Ethiopian Adult Population in a 2015 National Survey en_US
dc.type Journal Article en_US
ep.contributor.affiliation National References Laboratory for Clinical Chemistry, Ethiopian Public Health Institute, Addis Ababa, Ethiopia en_US
ep.contributor.affiliation ICAP-CU, Addis Ababa, Ethiopia en_US
ep.contributor.affiliation Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia en_US
ep.contributor.affiliation Department of Biochemistry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia en_US
ep.contributor.affiliation Ethiopian Biotechnology Institute, Addis Ababa, Ethiopia en_US
ep.contributor.affiliation Health System and Reproductive Health Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia en_US
ep.contributor.affiliation Center for Food Science and Nutrition, College of Natural Sciences, Addis Ababa University, Addis Ababa, Ethiopia en_US
ep.identifier.status Open Access en_US
ep.identifier.doi doi.org/10.1155/2020/9210261 en_US
ep.journal BioMed Research International en_US
ep.volume 7 en_US


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