dc.contributor.author |
Binkley, Laura |
|
dc.contributor.author |
Deressa, Asefa |
|
dc.contributor.author |
Shi, Mang |
|
dc.contributor.author |
Jara, Manuel |
|
dc.contributor.author |
E. Escobar, Luis |
|
dc.contributor.author |
R. Mauldin, Mathew |
|
dc.contributor.author |
Matheny, Audrey |
|
dc.contributor.author |
O’Quin, Jeanette |
|
dc.contributor.author |
G. Pieracci, Emily |
|
dc.contributor.author |
Kling, Chantal |
|
dc.contributor.author |
Hartloge, Yimer |
|
dc.contributor.author |
Abate, Ebba |
|
dc.contributor.author |
Gebreyes, Wondwossen |
|
dc.contributor.author |
Reynolds, Mary |
|
dc.contributor.author |
Belay, Ermias |
|
dc.contributor.author |
Shiferaw, Miriam |
|
dc.contributor.author |
Nakazawa, Yoshinori |
|
dc.contributor.author |
Velasco-Villa, Andres |
|
dc.date.accessioned |
2022-12-09T13:40:37Z |
|
dc.date.available |
2022-12-09T13:40:37Z |
|
dc.date.issued |
2021-09 |
|
dc.identifier.citation |
Laura Binkley, Asefa Deressa, Mang Shi, Manuel Jara, Luis E. Escobar, Mathew R. Mauldin, Audrey Matheny, Jeanette O'Quin, Emily G. Pieracci, Chantal Kling, Claire Hartloge, Getnet Yimer, Ebba Abate, Wondwossen Gebreyes, Mary Reynolds, Ermias Belay, Miriam Shiferaw, Yoshinori Nakazawa, Andres Velasco-Villa, Use of partial N-gene sequences as a tool to monitor progress on rabies control and elimination efforts in Ethiopia, Acta Tropica |
en_US |
dc.identifier.uri |
http://ephispace.ephi.gov.et/xmlui/handle/123456789/492 |
|
dc.description.abstract |
Ethiopia is one of the African countries most affected by rabies. A coarse catalog of rabies viruses (RABV) was
created as a benchmark to assess the impact of control and elimination activities. We evaluated a 726 bp
amplicon at the end of the N-gene to infer viral lineages in circulation using maximum likelihood and Bayesian
methods for phylogenetic reconstruction. We sequenced 228 brain samples from wild and domestic animals
collected in five Ethiopian regions during 2010–2017. Results identified co-circulating RABV lineages that are
causing recurrent spillover infections into wildlife and domestic animals. We found no evidence of importation of
RABVs from other African countries or vaccine-induced cases in the area studied. A divergent RABV lineage
might be involved in an independent rabies cycle in jackals. This investigation provides a feasible approach to
assess rabies control and elimination efforts in resource-limited countries. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Elsevier B.V. |
en_US |
dc.subject |
DOG RABIES |
en_US |
dc.subject |
CO-CIRCULATING LINEAGESRESOURCE |
en_US |
dc.subject |
MONITORING ELIMINATION |
en_US |
dc.title |
Use of partial N-gene sequences as a tool to monitor progress on rabies control and elimination efforts in Ethiopia |
en_US |
dc.type |
Journal Article |
en_US |
ep.contributor.affiliation |
Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA 30333, USA |
en_US |
ep.contributor.affiliation |
Ethiopian Public Health Institute, Gulele Sub City, Addis Ababa, Ethiopia |
en_US |
ep.contributor.affiliation |
Ohio State University Global One Health Initiative, Columbus, OH, USA |
en_US |
ep.contributor.affiliation |
Centre for Infection and Immunity Studies, School of Medicine, Sun Yat-Sen University, Guangzhou, China |
en_US |
ep.contributor.affiliation |
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA |
en_US |
ep.contributor.affiliation |
Department of Fish and Wildlife Conservation, Virginia Polytechnic Institute and State University, Blacksburg, VA 24601, USA |
en_US |
ep.identifier.status |
Open Access |
en_US |
ep.identifier.doi |
https://doi.org/10.1016/j.actatropica.2021.106022 |
en_US |
ep.journal |
Acta Tropica |
en_US |
ep.volume |
221 |
en_US |