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Severe vitamin A deficiency in a rural village in the Hararge region of Ethiopia

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dc.contributor.author Wolde-Gebriel, Zewdie
dc.contributor.author Gebru,Haile
dc.contributor.author Fisseha,Tezera,
dc.contributor.author West, Clive E.
dc.date.accessioned 2022-11-28T05:58:54Z
dc.date.available 2022-11-28T05:58:54Z
dc.date.issued 1993
dc.identifier.citation Wolde-Gebriel Z, Gebru H, Fisseha T, West CE. Severe vitamin A deficiency in a rural village in the Hararge region of Ethiopia. Eur J Clin Nutr. 1993 Feb;47(2):104-14
dc.identifier.uri http://172.21.6.100:8080/xmlui/handle/123456789/425
dc.description.abstract A Total of 240 children were examined for vitamin A deficiency in a village in Hararge region of Ethiopia. Night blindness, Bitot's spots, corneal xerosis, corneal ulceration and corneal scars were observed in 69, 16, 2, 15 and 14 children, respectively, based on the most severe eye signs. Blood was collected from 76 children with eye signs and 9 other children selected at random. The concentration of retinol (vitamin A) in serum was < 0.35 mumol/l in 30.2% of children and the median serum retinol-binding protein, iron, transferrin saturation and ferritin levels were low while the parameters of iodine status, total triiodothyronine, total thyroxine and thyrotropin, were all within the normal range. Levels of IgG and IgM were elevated in 78.8% and 82.4% children, respectively, while C-reactive protein levels were elevated in 42.4% of children. There was a higher prevalence of wasting (33%) than stunting (10%) with an additional 8% of children being both stunted and wasted. In the 2 years prior to the study, there were 74 deaths of which 17 were reported to be associated with ruptured corneas. The community had been dependent on relief food aid for the previous 6 years
dc.format.extent 104-114
dc.subject RURAL AREAS
dc.subject DIET
dc.subject XEROPHTHALMIA RETINOL
dc.subject HUMAN DISEASES
dc.subject ETHIOPIA
dc.subject DEVELOPING COUNTRIES
dc.title Severe vitamin A deficiency in a rural village in the Hararge region of Ethiopia
dc.type Journal Article
ep.identifier.status Limited access
ep.identifier.status Limited Access
ep.journal European Clinical Journal of Nutrition
ep.issue 2
ep.volume 47


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