Abstract:
Two new bisdesmosidic triterpenoid saponins were isolated, besides the three known saponins, from the MeOH ext. of the aerial parts of Achyranthes aspera LINN. (Amaranthaceae). Their structures were elucidated as β-D-glucopyranosyl 3β-[O-α-L-rhamnopyranosyl-(1→3)-O-β-D-glucopyranuronosyloxy]machaerinate (1) and β-D-glucopyranosyl 3β-[O-β-D-galactopyranosyl-(1→2)-O-α-D-glucopyranuronosyloxy]machaerinate (2) by NMR spectroscopy, including 2D-NMR expts. (machaerinic acid = 3β,21β-dihydroxyolean-12-en-28-oic acid). The other saponins were identified as β-D-glucopyranosyl 3β[O-α-L-rhamnopyranosyl-(1→3)-O-β-D-glucopyranuronosyloxy]oleanolate (3), β-D-glucopyranosyl 3-β-[O-β-D-galactopyranosyl-(1→2)-O-β-D-glucopyranuronosyloxy]oleanolate (4), and β-D-glucopyranosyl 3β-[O-β-D-glucopyranuronosyloxy]oleanolate (5) (oleanolic acid = 3β-hydroxyolean-12-en-28-oic acid). [on SciFinder(R)]
